Authors: Fatima DC. Jacinto-Calimag, MD, Ma. Corazon A. Iniego, MD, Ma. Angela M. Lavadia, MD, FPDS, Elizabeth P. Prieto, MD, FPDS
Background: Atopic Dermatitis is an emerging public health concern. Recently, several studies have explored the role of Vitamin D in atopic dermatitis. To date, there is no local study using Vitamin D supplementation as an adjunct in the treatment of atopic dermatitis.
Objective: To determine the efficacy of Vitamin D supplementation in improvement of the disease severity in atopic dermatitis patients.
Methods: This is a Randomized, double blind, placebo-controlled clinical trial. The participants are newly diagnosed atopic dermatitis patients aged 19 to 50 years old. Participants were randomly assigned to take either 1 capsule of oral Vitamin D supplement (2200 IU/capsule) or a comparable placebo capsule, once daily for 60 days. Vitamin D level and disease severity using SCORAD index was evaluated at the start and end of the study.
Results: The mean value of serum Vitamin D levels was deficient and comparable between the treatment and placebo group. The mean change in the serum Vitamin D levels of patients in the Treatment and Placebo group were 10.4 ng/mL ± 5.8 and -0.4 ng/mL ± 3.5, respectively. The mean change in the SCORAD index scores of patients in the Treatment and placebo group were -20.2 ± 20.6 and 2.2 ± 6.8, respectively. Result of the two-sample independent t-test showed that the mean change in the SCORAD index scores significantly varied according to treatment group (p<0.0001).
Conclusion: The results from this study indicate that vitamin D supplementation may ameliorate clinical signs of the disease and can be considered as a safe and well-tolerated form of therapy.
Atopic dermatitis, Vitamin D, SCORAD index, t-test
Authors: Katrina Carmela M. Belen, MD, DPDS, Jasmin J.Jamora, MD, FPDS , Ma. Cecilia P. Ingente MD, DPDSAbstractBackground: Dermoscopy, a non-invasive diagnostic tool, has been proven to improve the diagnostic accuracy of vascular tumors since it can aid in...
A randomized, double-blind, comparative study on the safety and efficacy of virgin coconut (Cocos nucifera l.) oil against 1% hydrocortisone lotion as an anti-inflammatory and antipruritic preparation for mosquito reactions
Authors: Uy, Veronica S, MD; Gracia B. Teodosio, MD, FPDS; Ma. Teresita G. Gabriel, MD, FPDS; Mary Catherine T. Galang, MD; Mohammad Yoga A. Waskito, MD; Johannes F. Dayrit, MD, FPDS Abstract Background: Virgin coconut oil (VCO) has been reported...
Primary Cutaneous Anaplastic Large Cell Lymphoma (PC-ALCL) is a rare Non-Hodgkin lymphoma (NHL) representing approximately 9% of all cutaneous lymphomas.3 It usually manifests as a slow-growing, solitary tumor which has a tendency to regress spontaneously. However, metastasis is reported in 5-10% of cases.