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Demographic and clinical profiles of adult Filipino patients with psoriasis in Davao City: A cross sectional study

Janice Natasha C. Ng, MD; Bryan Edgar G. Guevara, MD, DPDS; Victoria P. Guillano, MD, FPDS

Abstract

Background:

The Psoriasis Registry (PsorReg) was created by the Psoriasis Foundation of the Philippines with the goal of assessing the true magnitude of psoriasis in Davao City.

 

Objectives:

To determine the demographic and clinical profiles of Filipino patients enrolled in PsorReg.

 

Methods:

Cross-sectional study among adult patients enrolled in PsorReg.

 

Results:

A total of 131 patients were included in the study. Mean age was 43.89 ± 15.8 years old. Chronic plaque psoriasis (96.2%) was the most common clinical pattern. 63.4% had nail involvement, while 35.1% had psoriatic arthritis. BMI was normal in 51.1% of patients. Common co-morbidities were hypertension (19.1%), diabetes (10.7%), and dyslipidemia (9.2%). Most common treatment were topical medications, while biologics were the least common. 42.7%, 49.6% and 37.4% had moderate psoriasis using BSA, PASI, and PGA, respectively. Majority (47.3%) reported a large effect of psoriasis on their quality of life.

 

Conclusion:

This study determined the demographic and clinical profiles of adult Filipino patients registered in PsorReg in Davao City.

References

  1. Rachakonda TD, Schupp CW, Armstrong AW. Psoriasis prevalence among adults in the United States. J Am Acad Dermatol. 2014;70(3):512-6.
  2. Takeshita J, Grewal S, Langan SM, Mehta NN, Ogdie A, Van Voorhees AS, et al. Psoriasis and comorbid diseases: Epidemiology. J Am Acad Dermatol. 2017;76(3):377-90.
  3. Global report on psoriasis: World Health Organization; 2016.
  4. Philippine Dermatological Society Health Information Systems. Philippine Dermatological Society. c2011 [updated July 20, 2016; cited July 30, 2016]. Available by request from: pdshis@outlook.com
  5. Davidovici BB, Sattar N, Prinz J, Puig L, Emery P, Barker JN, et al. Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions. J Invest Dermatol. 2010;130(7):1785-96.
  6. Langley RG, Krueger GG, Griffiths CE. Psoriasis: epidemiology, clinical features, and quality of life. Ann Rheum Dis. 2005; 64(suppl 2):ii18-23.
  7. Gudjonsson JE. Psoriasis. In: Goldsmith LA, Katz SI, Gilchrest BA, Palier AS, Leffell DJ and Wolff K, eds. Fitzpatrick’s Dermatology in General Medicine. 8th ed. New York, NY: McGraw-Hill Companies, Inc; 2012:197.
  8. Puig L, Julia A, Marsal S. The pathogenesis and genetics of psoriasis. Actas Dermosifiliogr. 2014;105(6):535-45.
  9. Lowes MA, Bowcock AM, Krueger JG. Pathogenesis and therapy of psoriasis. Nature. 2007;445(7130):866-73.
  10. Kho J, Pacheco C, Serrano MA. Epidemiological survey of psoriasis: clinical profile of 54 club members of the psoriasis foundation of the Philippines (Davao Medical Center’s Department of Dermatology): A preliminary report. J Phil Soc Cut Med. 2001;2: 40-46.
  11. Tolentino JR, Dizon J. Sociodemographic and clinical profiles of psoriasis in Ospital ng Maynila Medical Center (1995-1999): A Retrospective Study. J Phil Soc Cut Med. 2003; 4: 71-77.
  12. Loo CH, Chan YC, Lee KQ, Tharmalingam P, Tan WC. Clinical profile, morbidity and outcome of adult patients with psoriasis at a district hospital in Northern Malaysia. Med J Malaysia. 2015;70(3):177-81.
  13. Henseler T, Christophers E. Psoriasis of early and late onset: characterization of two types of psoriasis vulgaris. J Am Acad Dermatol. 1985;13(3):450-6.
  14. Chularojanamontri L, Kulthanan K, Suthipinittharm P, Jiamton S, Wongpraparut C, Silpa-Archa N, et al. Clinical differences between early- and late-onset psoriasis in Thai patients. Int J Dermatol. 2015;54(3):290-4.
  15. Ferrandiz C, Pujol RM, Garcia-Patos V, Bordas X, Smandia JA. Psoriasis of early and late onset: a clinical and epidemiologic study from Spain. J Am Acad Dermatol. 2002;46(6):867-73.
  16. Coimbra S, Oliveira H, Figueiredo A, Rocha-Pereira P, Santos-Silva A. Psoriasis: Epidemiology, Clinical and Histological Features, Triggering Factors, Assessment of Severity and Psychosocial Aspects. In Psoriasis-A Systemic Disease [Internet]. 2012.
  17. Chang CC, Gangaram HB, Hussein SH. Malaysian Psoriasis Registry–preliminary report of a pilot study using a newly revised registry form. Med J Malaysia. 2008;63 Suppl C:68-71.
  18. Armstrong AW, Harskamp CT, Dhillon JS, Armstrong EJ. Psoriasis and smoking: a systematic review and meta-analysis. Br J Dermatol. 2014;170(2):304-14.
  19. Carrascosa JM, Rocamora V, Fernandez-Torres RM, Jimenez-Puya R, Moreno JC, Coll-Puigserver N, et al. Obesity and psoriasis: inflammatory nature of obesity, relationship between psoriasis and obesity, and therapeutic implications. Actas Dermosifiliogr. 2014;105(1):31-44.
  20. Baeta IG, Bittencourt FV, Gontijo B, Goulart EM, Karoli R, Fatima J, et al. Comorbidities and cardiovascular risk factors in patients with psoriasis. An Bras Dermatol. 2014;89(5):735-44.
  21. Bedi TR. Clinical profile of psoriasis in North India. Indian J Dermatol Venereol Leprol. 1995;61(4):202-5.
  22. Ryan C, Korman NJ, Gelfand JM, Lim HW, Elmets CA, Feldman SR, et al. Research gaps in psoriasis: opportunities for future studies. J Am Acad Dermatol. 2014;70(1):146-67.
  23. Akaraphanth R, Kwangsukstid O, Gritiyarangsan P, Swanpanyalert N. Psoriasis registry in public health hospital. J Med Assoc Thai. 2013;96(8):960-6.
  24. Norredam M, Kastrup M, Helweg-Larsen K. Register-based studies on migration, ethnicity, and health. Scand J Public Health. 2011;39(7 Suppl):201-5.
  25. Rice HE, Englum BR, Gulack BC, Adibe OO, Tracy ET, Kreissman SG, et al. Use of patient registries and administrative datasets for the study of pediatric cancer. Pediatr Blood Cancer. 2015;62(9):1495-500.
  26. Taruscio D, Gainotti S, Mollo E, Vittozzi L, Bianchi F, Ensini M, et al. The current situation and needs of rare disease registries in Europe. Public Health Genomics. 2013;16(6):288-98.
  27. DiMarco G, Hill D, Feldman SR. Review of patient registries in dermatology. J Am Acad Dermatol. 2016;75(4):824-9.
  28. de Souza MP, Rangel Miller V. Significance of patient registries for dermatological disorders. J Invest Dermatol. 2012;132(7):1749-52.
  29. Michalek IM, Loring B, John SM. A systematic review of worldwide epidemiology of psoriasis. J Eur Acad Dermatol Venereol. 2017;31(2):205-12.
  30. Gelfand JM, Stern RS, Nijsten T, Feldman SR, Thomas J, Kist J, et al. The prevalence of psoriasis in African Americans: results from a population-based study. J Am Acad Dermatol. 2005;52(1):23-6.
  31. Moradi M, Rencz F, Brodszky V, Moradi A, Balogh O, Gulacsi L. Health status and quality of life in patients with psoriasis: an Iranian cross-sectional survey. Arch Iran Med. 2015;18(3):153-9.
  32. Jiamton S, Suthipinittharm P, Kulthanan K, Chularojanamontri L, Wongpraparut C, Silpa-archa N, et al. Clinical characteristics of Thai patients with psoriasis. J Med Assoc Thai. 2012;95(6):795-801.
  33. Queiro R, Tejon P, Alonso S, Coto P. Age at disease onset: a key factor for understanding psoriatic disease. Rheumatology. 2014;53(7):1178-85.
  34. Harden JL, Krueger JG, Bowcock AM. The immunogenetics of Psoriasis: A comprehensive review. J Autoimmun. 2015;64:66-73.
  35. Oliveira Mde F, Rocha Bde O, Duarte GV. Psoriasis: classical and emerging comorbidities. An Bras Dermatol. 2015;90(1):9-20.
  36. Lee MS, Lin RY, Lai MS. Increased risk of diabetes mellitus in relation to the severity of psoriasis, concomitant medication, and comorbidity: a nationwide population-based cohort study. J Am Acad Dermatol. 2014;70(4):691-8.
  37. Jacobi A, Kupke C, Behzad M, Hertl M. Comorbidities, metabolic risk profile and health-related quality of life in German patients with plaque-type psoriasis: a cross-sectional prospective study. Int J Dermatol. 2013;52(9):1081-7.
  38. Mazlin MB, Chang CC, Baba R. Comorbidities associated with psoriasis – data from the malaysian psoriasis registry. Med J Malaysia. 2012;67(5):518-21.
  39. Tseng HW, Lin HS, Lam HC. Co-morbidities in psoriasis: a hospital-based case-control study. J Eur Acad Dermatol Venereol. 2013;27(11):1417-25.

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Demographic and clinical profiles of adult Filipino patients with psoriasis in Davao City: A cross sectional study