Authors: Patricia Gaile E. Espinosa, MD1, Rogelio A. Balagat, MD, FPCP, FPDS, FPRA
Introduction: The occurrence of generalized discoid lupus erythematosus (DLE) and myelopathy has not been reported to date. DLE in the context of systemic lupus erythematosus (SLE) is considered to have a more benign prognosis. Among the subsets of cutaneous lupus erythematosus (CLE), DLE is the least likely to progress to SLE. Less than 5% of DLE cases progress to SLE. We report a 19-year-old woman who presented with generalized DLE and myelopathy.
Case Summary: This is a case of a 19-year-old woman who presented with non-pruritic red circumscribed plaques on the face, ears, and arms, with some showing scarring, telangiectasia, and pigmentation. Three months later, she developed paraplegia, an inability to urinate and defecate, and a sensory loss up to the level of T10. Findings on skin biopsy, a positive antinuclear antibody (ANA), and transverse myelitis on MRI all confirm the presence of SLE.
Conclusion: DLE has 2 subtypes, localized and generalized, which affect body areas above and below the neck. Generalized DLE poses a higher risk for developing SLE (15-28%) compared to localized DLE (5-10%). Myelopathy is a rare presentation in SLE, occurring in only 1-2% of cases. Although this has not been reported before, it is possible for generalized DLE and myelopathy to co-exist. The presence of generalized DLE is a marker of a poor clinical outcome.
generalized discoid, lupus erythematosus, myelopathy
Authors: Katrina Carmela M. Belen, MD, DPDS, Jasmin J.Jamora, MD, FPDS , Ma. Cecilia P. Ingente MD, DPDSAbstractBackground: Dermoscopy, a non-invasive diagnostic tool, has been proven to improve the diagnostic accuracy of vascular tumors since it can aid in...
A randomized, double-blind, comparative study on the safety and efficacy of virgin coconut (Cocos nucifera l.) oil against 1% hydrocortisone lotion as an anti-inflammatory and antipruritic preparation for mosquito reactions
Authors: Uy, Veronica S, MD; Gracia B. Teodosio, MD, FPDS; Ma. Teresita G. Gabriel, MD, FPDS; Mary Catherine T. Galang, MD; Mohammad Yoga A. Waskito, MD; Johannes F. Dayrit, MD, FPDS Abstract Background: Virgin coconut oil (VCO) has been reported...
Primary Cutaneous Anaplastic Large Cell Lymphoma (PC-ALCL) is a rare Non-Hodgkin lymphoma (NHL) representing approximately 9% of all cutaneous lymphomas.3 It usually manifests as a slow-growing, solitary tumor which has a tendency to regress spontaneously. However, metastasis is reported in 5-10% of cases.