May 2017 Case Reports


A novel mutation in the EDA gene in a Filipino family with X-linked hypohidrotic ectodermal dysplasia

A novel mutation in the EDA gene in a Filipino family with X-linked hypohidrotic ectodermal dysplasia

Bryan Edgar K. Guevara,MD, Maria Vinna N. Crisostomo,MD, Chao-Kai Hsu,MD, Lu Liu,MD, Maria Mercedes S. Cauilan, MD, FPDS and John A. McGrath, MD, FRCP, FMedSci

X-linked hypohidrotic ectodermal dysplasia (XLHED) is a rare genetic disorder that affects the development and function of several structures of ectodermal origin, such as hair, teeth and sweat glands. It is associated to ectodysplasin-A (EDA) gene mutation, necessary for ectodermal development.

Allergic contact dermatitis to propolis presenting as tinea pedis

Allergic contact dermatitis to propolis presenting as tinea pedis

John Michael F. Dellariarte, MD; Shereen Reine S. Rodriguez, MD and Vermen M. Verallo-Rowell, MD, FPDS

Allergic contact dermatitis (ACD) is a common dermatologic condition. ACD may present with a typical clinical presentations, requiring patch testing for diagnosis. A 77-year-old Filipino female presented with a 6 month-history of bilateral symmetrical pruritic scaly plaques on both feet diagnosed and treated as a case tinea pedis unresponsive to topical antifungal treatment. Patch test result was positive for Propolis

Bubbly lupus: A case of a Filipino woman with bullous systemic lupus erythematosus successfully treated with prednisone and hydroxychloroquine

Bubbly lupus: A case of a Filipino woman with bullous systemic lupus erythematosus successfully treated with prednisone and hydroxychloroquine

Grace Monica P. Ibaviosa, MD; Johanna O. Flordelis, MD and Johannes F. Dayrit, MD, FPDS

Bullous systemic lupus erythematosus (BSLE) is an autoimmune-mediated, chronic, widespread, non-scarring, sub-epidermal blistering skin disease. It is typically caused by autoantibodies against type VII collagen. BSLE is an uncommon manifestation of SLE and is found in less than 5% of SLE cases.