Bryan Edgar K. Guevara,MD, Maria Vinna N. Crisostomo,MD, Chao-Kai Hsu,MD, Lu Liu,MD, Maria Mercedes S. Cauilan, MD, FPDS and John A. McGrath, MD, FRCP, FMedSci
X-linked hypohidrotic ectodermal dysplasia (XLHED) is a rare genetic disorder that affects the development and function of several structures of ectodermal origin, such as hair, teeth and sweat glands. It is associated to ectodysplasin-A (EDA) gene mutation, necessary for ectodermal development.
John Michael F. Dellariarte, MD; Shereen Reine S. Rodriguez, MD and Vermen M. Verallo-Rowell, MD, FPDS
Allergic contact dermatitis (ACD) is a common dermatologic condition. ACD may present with a typical clinical presentations, requiring patch testing for diagnosis. A 77-year-old Filipino female presented with a 6 month-history of bilateral symmetrical pruritic scaly plaques on both feet diagnosed and treated as a case tinea pedis unresponsive to topical antifungal treatment. Patch test result was positive for Propolis
Jennifer Aileen Ang-Tangtatco, MD, DPDS; Karen Lee Alabado, MD, FPDS and Lalaine Visitacion, MD, FPDS
Arsenic is categorized as a class I human carcinogen by the International Agency for Research on Cancer and chronic exposure to its inorganic form have been associated with a variety of diseases.
Grace Monica P. Ibaviosa, MD; Johanna O. Flordelis, MD and Johannes F. Dayrit, MD, FPDS
Bullous systemic lupus erythematosus (BSLE) is an autoimmune-mediated, chronic, widespread, non-scarring, sub-epidermal blistering skin disease. It is typically caused by autoantibodies against type VII collagen. BSLE is an uncommon manifestation of SLE and is found in less than 5% of SLE cases.
Mary Rose Lim-del Mindo MD, DPDS and Daisy King-Ismael MD, FPDS
Pyoderma gangrenosum (PG) is a rare, inflammatory, ulcerative skin condition characterized by an ulcer with advancing violaceous border, negative cultures, unresponsiveness to antibiotics, the phenomenon of pathergy and histopathology showing neutrophilic infiltration.
Jessica Nohealani Marie J. Brillantes-Quiazon, MD and Claudine B. Yap-Silva, MD, FPDS
Pachydermoperiostosis is a rare genetic disorder. The pathophysiology remains incompletely understood, and various patterns of inheritance have been proposed: autosomal dominant, autosomal recessive and x-linked. Variable penetrance has also been observed.