Authors: Marilie E. Araojo, Benedicto dL. Carpio, Eileen Regalado-Morales, Ma. May Jasmin Ramos-Yason


Leiomyoma is a benign cutaneous neoplasm of smooth muscle. The pathogenesis has yet to be determined. Most leiomyomas are acquired but can be hereditary. Leiomyoma presents as solitary to multiple skin colored papules and nodules. In this case report, a 19-year-old Filipino female presented with two years history of papules and nodules on the abdomen. There were no associated symptoms such as pain or pruritus. No consult or medication applied. Lesions gradually increased in size and number spreading on the neck, abdomen, trunk and thighs. Persistence of the lesions prompted consult in Ospital ng Maynila Medical Center, Manila, Philippines. She was initially diagnosed with Multiple Neurofibroma. Excision biopsy of the lesion was done. She was prescribed with Cefuroxime 500 mg capsule, 1 capsule twice a day for 7 days, Mupirocin 2% ointment twice a day for 7 days.  Histopathology reveals that the lesion is hemispherical, the epidermis is normal. In the dermis there is an ill-defined tumor composed of broad bundles of smooth muscles and interlacing fascicles of eosinophilic spindle cells, eosinophilic interlacing bundles and irregular collections of elongated cells with bright eosinophilic cytoplasm and blunt-ended (cigar-shaped) nuclei are seen. The histopathology diagnosis is Leiomyoma, multiple, (Piloleiomyoma, probable).The patient was advised for surgical excision.





Leiomyoma, benign, neooplasm, smooth muscle

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