(Last Updated On: October 29, 2018)

Authors: Maynie Bambi D. Lugasan, Camille Joyce J. Crisostomo, Karen Lee Alabado-Laurel


Introduction: Mycosis fungoides is the most common among the cutaneous T-cell lymphomas. It typically starts either as a patch or plaque and may evolve into a tumor which may spontaneously ulcerate. We present a case of mycosis fungoides mimicking squamous cell carcinoma in a 38-year old female.

Case summary: This is a case of a 38-year old female who presented with a solitary, well-demarcated, 20 x 16 cm ulcer, topped with necrotic crust on the distal left lower extremity noted two years prior to consult. A fixed, non-movable, 1 cm left inguinal lymph node was noted. Routine histopathology and immunohistochemical tests done were consistent with mycosis fungoides. Dermatologic management focused on proper wound care, antibiotic therapy and supportive measures to decrease the tumor burden of the patient. She was referred to radiologic oncology for radiotherapy.

Conclusion: Mycosis fungoides is a differential diagnosis in patients presenting with chronic non-healing ulcers. This case highlights the importance of clinico-histopathologic correlation in diagnosing cases mimicking another condition.





mycosis fungoides, squamous cell carcinoma, immunohistochemistry, radiotherapy

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