November 2017 Systematic Review and Meta-analysis

Non-MDT treatment for paucibacillary leprosy: a systematic review and meta-analysis of randomized controlled trials

Cybill Dianne C. Uy, MD1, Erin Jane L. Tababa, MD1, Belen L. Dofitas, MD

Leprosy continues to pose a public health problem, especially in developing countries. Although the overall incidence of newly diagnosed cases have declined significantly, the rate of decline has been static. This static rate of decline, and an increasing number of persister cases and relapses, are thought to be brought about by increasing antibiotic resistance.