Nov 2018 Supplemental Issue Ichthyoses

Epidermolytic Hyperkeratosis with Significant Improvement in Quality of Life after Treatment with Acitretin

Christeven Tanamas, MD, Elisabeth Ryan, MD, Ricky H. Hipolito, MD, DPDS

Epidermolytic hyperkeratosis (EH) is a rare and severe form of ichthyosis with occurrence in 1 of 300,000 persons. EH is an autosomal dominant condition caused by mutations in keratin 1 and keratin 10. Few published literature owing to the rarity of the condition has limited the treatment options for EH. Traditional management with emollients are unsatisfactory in relieving the concerns of the patients, including the odor attributed to bacterial colonization, skin thickness and hyperpigmentation. EH is a severely debilitating disorder impairing the personal, social and economic activities of patients affected, further adding to the cost of management.

A rare case of Confluent and Reticulated Papillomatosis of Gougerot and Carteaud in a 23-year old male treated with Doxycycline

Alyssa Joyce L. Cuadra, MD, Audi, MD, Elizabeth Ryan, MD, Leilani Senador, MD

Confluent and Reticulated Papillomatosis is a rare disease seen in young adults characterized by persistent brown scaly papules that are confluent in the center and reticulated in the periphery distributed mainly on the neck, upper trunk and axillae. It is an acquired Ichthyosiform dermatosis. Misdiagnosis is frequent for it resembles lesions like that of Tinea Versicolor. Different treatment approaches have been use such as keratolytics and antibiotics. But Minocycline is still the first-line of treatment supporting that the condition is caused by an infection or inflammation.