Nov 2018 Supplemental Issue Malignant Tumors


An invasive variant of mammary Paget disease in a Filipino woman with breast carcinoma

Paola S. Young, MD, Ma. Celina C. Gonzales, MD, Felix Paolo J. Lizarondo, MD, Eileen A. Cubillan, MD, FPDS

Paget disease of the breast is considered to be a ductal carcinoma in situ from the lactiferous duct extending to the nipple epidermis, without invading the basement membrane in majority of cases. Only a few cases of the invasive type of mammary Paget disease have been documented in literature.

Pigmented Nodular Basal Cell Carcinoma from a Congenital Melanocytic Nevus in a 68-year old female

Angela E. Sison MD, Joanne Kate M. Martinez MD, Karla Phoebe B. Castaños MD

Basal cell carcinoma (BCC) is the most common skin malignancy seen in sun-exposed areas. Pigmented nodular basal cell carcinoma (PBCC) is a clinical and histologic variant of BCC. Aside from displaying features seen in nodular BCC, it also contains increased brown or black pigment, the presence of which makes it necessary to rule out melanoma. Congenital melanocytic nevi (CMN), on the other hand, are common skin lesions that carry a risk of malignant transformation, especially melanoma.

Clinical, Dermoscopic and Histopathological Features of Pigmented Basal Cell Carcinoma in Filipinos: A Series of 20 Cases

Elisabeth Ryan, MD, Marie Claudine Francesca B. Perlas, MD, Johannes F. Dayrit, MD, FPDS

Basal Cell Carcinoma (BCC) is the most frequent skin malignancy of all cases of non-melanoma skin cancer. Diagnosis is through clinical and histopathologic confirmation. While biopsy is the gold standard, dermoscopy is valuable in the immediate recognition of the pigmented type of BCC in brown, Filipino skin.

A rose by any other name: squamous cell carcinoma of the vulva

Miyahra Haniko P. Lopez, MD-MBA, Jacqueline Delas Alas Melendres, MD, FPDS

Dermatoses affecting the genitals may be of infectious, inflammatory, or neoplastic cause, and can be simply confined to the genitalia or a manifestation of a more widespread condition. Patients with cutaneous diseases of the external genitalia often initially present to their primary care provider which may be a dermatologist.

Mimickers of Malignancy – Epithelial Tumors Mimicking Angiosarcoma: A Case Series

Katrina Erika R. Habaluyas, MD-MBA, Cynthia Ciriaco-Tan, MD, FPDS

Angiosarcoma is a rare aggressive malignant tumor of endothelial cell origin, with a predilection for the skin and superficial soft tissues (50% affecting the head and neck). Early diagnosis is imperative to facilitate proper management and increase overall survival rate, given its high rate of metastasis.