Reagan Grey T. Reyes, MD; Krisinda Clare C. Dirn-Jarnora, MD, FPDS
Merkel cell carcinoma (MCC) is an aggressive dermal tumor of neuroendocrine origin. It is a rare, highly malignant primary skin tumor, with approximately 2,000 cases reported. This malignancy poses a challenge to clinicians due to its rarity and poor prognosis.
Felina Joyce Posadas Dy, MD; Marian Caligayahan, MD; Cynthia Tan, MD, FPDS
Behcet’s disease has been described to be both an autoimmune and an autoinflammarotory disorder. Recurrent oral aphthous ulcers characterize this disease, usually with the involvement of other organ systems including dermatologic manifestations. Due to its ability to involve blood vessels, vasculitis is the usual finding.
Jennica Celine S. Ponce, MD; Ma. Flordeliz A. Casintahan, MD, FPDS; Margaret Mary B. Alegre, MD, DPDS
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematodermic malignancy that usually occurs in elderly individuals and manifests with skin lesions followed by involvement of lymph nodes, bone marrow, and peripheral blood. There is a high risk for leukemic dissemination, hence, a poor prognosis.
Marie Claudine Francesca B. Perlas, MD, Johannes F. Dayrit, MD, FPDS, Maria Teresita G. Gabriel, MD, FPDS, Cara Lynn Marie N. Chia, MD
Sezary syndrome is an extremely rare leukemic cutaneous T cell lymphoma, with annual incidence of 0.3 to 1 per 100,000, characterized by triad of erythroderma, lymphadenopathy, and circulating Sézary cells in the peripheral blood.
Patricia Angelica Pastrana-Mabanta, MD, MBA, Ma. Jasmin J. Jamora, MD, FPDS, Mae Ramirez-Quizon MD, FPDS
Epidermolysis Bullosa, Generalized-Severe (EBS-gen sev) is a rare genodermatosis, resulting from multiple gene mutations, characterized by marked mechanical skin fragility. It presents at birth with disseminated friction-induced blistering. Erosions heal without scarring and lesions tend to improve with age.
Athena Emmanuelle M. Parro, MD, Patricia Anne Nicole Ramirez- Ecarma, MD, Arunee H. Sirpunvarapon- Dela Cruz, MD, FPDS
Confluent and reticulated papillomatosis (CARP), also known as Gougerout-Carteaud Syndrome, is a rare disease affecting young adults. It is often characterized by asymptomatic hyperpigmented papules coalescing into confluent patches and plaques centrally and exhibiting a reticular pattern peripherally.