Schimmelpenning syndrome may encompass abnormalities of the cardiovascular, skeletal, ophthalmologic and urogenital systems. Nevus sebaceous is a hallmark finding and ophthalmologic findings are seen in 59% of the cases which include colobomas and choristomas.
Cushing syndrome caused by application of topical corticosteroids is rarely reported. Systemic side effects like suppression of hypothalamic-pituitary-adrenal axis, growth retardation in children and iatrogenic Cushing syndrome can occur even in small doses of potent topical steroids.1
Behçet’s disease is a chronic multisystem disease that is characterized by vasculitis. Recurrent oral aphthous ulcers, genital ulcers, skin and ocular lesions, and arthritis are the most frequent clinical manifestations. Pathergy may or may not be present. Due to its distinct clinical presentation, knowledge and clinical expertise are needed in order to promptly establish the diagnosis and address the disease. We report two cases of Behcet’s Disease in 2 Filipinos on the basis of history, clinical presentation, and supported by skin punch biopsy findings.
Hemochromatosis is a hereditary or acquired chronic iron overload syndrome that presents with organ damage to the liver, pancreas, heart, joints and skin due to pathologic iron deposition. Hereditary hemochromatosis is a common genetic disorder with human hemochromatosis protein (HFE) mutations found in European ethnic groups but has low-prevalence in the Asian population.
Cutaneous leishmaniasis is non-endemic in the Philippines. Antiparasitic pentavalent antimonials are acknowledged as first-line therapy for all forms of the disease. Amphotericin B is the second drug of choice but its use is limited due to side effects.