Authors: Maria Kristina R. Fajardo, MD, Daisy King-Ismael, MD, FPDS,Bernardita O. Policarpio, MD, FPDS
INTRODUCTION :Syringocystadenoma papilliferum (SCAP) is a relatively rare benign adnexal skin tumor which can manifest in a
variety of clinical forms. Nearly one-third of cases are known to develop within a pre-existing nevus sebaceus (NS). The peculiar
feature of this case was the appearance of a large exophytic tumor within a congenital verrucous plaque, which raised the
suspicion of a malignant transformation. This is a case of a young Filipino adult with an unusual presentation of syringocystadenoma papilliferum in a nevus sebaceus mimicking squamous cell carcinoma.
CASE REPORT: A 27-year-old Filipino female presented a persistently enlarging exophytic pedunculated cribriform tumor within
a congenital verrucous plaque on the left temporal area. The tumor started to appear when she was 20 years old. One month
prior to consult, it rapidly increased in size and bled on gentle manipulation. She has neither comorbidities nor any family history
of a similar condition. Her physical examination was normal, with no palpable lymphadenopathies. The biopsy showed syringocystadenoma papilliferum on a nevus sebaceus. She underwent carbon dioxide (CO2) laser excision under local anesthesia. The procedure was uneventful and the patient is on regular follow-up and close monitoring for any possible malignant change or recurrence.
CONCLUSION:A case of syringocystadenoma papilliferum on a nevus sebaceus mimicking squamous cell carcinoma in a Filipino
female treated with carbon dioxide laser excision was presented. The unusual presentation of SCAP can mimic malignancy and
histopathologic evaluation is warranted to rule out malignant transformation for proper management.
KEYWORDS: Syringocystadenoma papilliferum, secondary tumors, nevus sebaceu
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