Introduction: Basal cell nevus syndrome is a rare autosomal dominant disorder with a prevalence ranging from 1 in 60,000 to 1 in 120,000. It is associated with a panoply of abnormalities including developmental anomalies and postnatal tumors such as basal cell carcinoma.
Case summary: We report a 50-year old Filipina who suffered from multiple recurrent pigmented papules and plaques on the face, first appearing at age 20. Some lesions enlarged into tumors and spontaneously bled and ulcerate. She underwent 2 excisions 21 years apart, each time showing the same histopathological report of basal cell carcinoma. Her mother had basal cell carcinoma. Both her hands showed palmar pits. She had a bifid left 3rd rib on chest x-ray. A skin biopsy also showed basal cell carcinoma.
Conclusion: This case illustrates how a case of basal cell nevus syndrome was diagnosed: basal cell carcinoma at a young age, a first-degree relative with the same tumor, palmar pits, and a bifid rib. Suspect basal cell nevus syndrome in a patient with multiple basal cell carcinoma arising at an early age.
Basal Cell Nevus Syndrome; Basal Cell Carcinoma; Gorlin Syndrome
Authors: Katrina Carmela M. Belen, MD, DPDS, Jasmin J.Jamora, MD, FPDS , Ma. Cecilia P. Ingente MD, DPDSAbstractBackground: Dermoscopy, a non-invasive diagnostic tool, has been proven to improve the diagnostic accuracy of vascular tumors since it can aid in...
A randomized, double-blind, comparative study on the safety and efficacy of virgin coconut (Cocos nucifera l.) oil against 1% hydrocortisone lotion as an anti-inflammatory and antipruritic preparation for mosquito reactions
Authors: Uy, Veronica S, MD; Gracia B. Teodosio, MD, FPDS; Ma. Teresita G. Gabriel, MD, FPDS; Mary Catherine T. Galang, MD; Mohammad Yoga A. Waskito, MD; Johannes F. Dayrit, MD, FPDS Abstract Background: Virgin coconut oil (VCO) has been reported...
Primary Cutaneous Anaplastic Large Cell Lymphoma (PC-ALCL) is a rare Non-Hodgkin lymphoma (NHL) representing approximately 9% of all cutaneous lymphomas.3 It usually manifests as a slow-growing, solitary tumor which has a tendency to regress spontaneously. However, metastasis is reported in 5-10% of cases.