Authors: Bryan Edgar K. Guevara MD, Wei-Ting Tu MD, Ping-Chen Hou, Hsin-Yu Huang MD, Jessica Chen MD, Chao-Kai Hsu MD
The new era of molecular diagnostics has provided new insights in both routine clinical work and research in hereditary epidermolysis bullosa (EB). Several different approaches and techniques have provided significant advantages in terms of diagnostic accuracy, predicting prognoses, clarifying the pathogenesis, and developing new therapies. In many developing countries, however, modern laboratory techniques remain inaccessible. Therefore, a practical diagnostic matrix has been developed to predict the diagnosis and subtype of EB. In this review, we highlight the molecular and practical techniques in diagnosing hereditary EB
Guevara BEK, Tu WT, Hou PC, Huang HY, Chen J, Hsu CK. The practical diagnostic approach for hereditary epidermolysis bullosa in the era of next generation sequencing. J Phil Dermatol Soc 2019, 28(1), 6-9
Figure 1. The patient manifesting with multiple blisters, erosions, and atrophic scars
epidermolysis bullosa, molecular genetics, genodermatoses
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Authors: Katrina Carmela M. Belen, MD, DPDS, Jasmin J.Jamora, MD, FPDS , Ma. Cecilia P. Ingente MD, DPDSAbstractBackground: Dermoscopy, a non-invasive diagnostic tool, has been proven to improve the diagnostic accuracy of vascular tumors since it can aid in...
A randomized, double-blind, comparative study on the safety and efficacy of virgin coconut (Cocos nucifera l.) oil against 1% hydrocortisone lotion as an anti-inflammatory and antipruritic preparation for mosquito reactions
Authors: Uy, Veronica S, MD; Gracia B. Teodosio, MD, FPDS; Ma. Teresita G. Gabriel, MD, FPDS; Mary Catherine T. Galang, MD; Mohammad Yoga A. Waskito, MD; Johannes F. Dayrit, MD, FPDS Abstract Background: Virgin coconut oil (VCO) has been reported...
Primary Cutaneous Anaplastic Large Cell Lymphoma (PC-ALCL) is a rare Non-Hodgkin lymphoma (NHL) representing approximately 9% of all cutaneous lymphomas.3 It usually manifests as a slow-growing, solitary tumor which has a tendency to regress spontaneously. However, metastasis is reported in 5-10% of cases.