Authors: Astri Melistri, Irene Djuardi, Idrianti Idrus, Muji Iswanty, Faridha Ilyas
Introduction: Toxic Epidermal Necrolysis (TEN) is acute mucocutaneous reaction characterized with extensive necrosis of epidermis. It is the highest grade of SJS-TEN clinical spectrum, involving necrosis of >30% of body surface area. It is also associated with mucosal membrane. The etiology and risk factor for adult are drug use and malignancy while the etiology for children is infection.
Case Summary: Reported one case of TEN in a woman, 40 years old, comes with chief complain exfoliated skin since 3 days ago and skin disorder that arises in the form of generalized blistering and macular erythema, there is erosion of the lips and conjunctivitis. The patient have history of malignant lymphoma since 5 years ago. The patient respond well to supportive therapy and systemic corticosteroid.
Conclusion: The diagnosis is made based on history, clinical features, laboratory examinations, and skin biopsy. Malignancy is known to be associated with an increased mortality rate in patients with TEN. However, risk factors contributing to the poor prognosis of patients with TEN with malignancies remain undefined.
corticosteroid, malignant, toxic epidermal necrolysis
Authors: Katrina Carmela M. Belen, MD, DPDS, Jasmin J.Jamora, MD, FPDS , Ma. Cecilia P. Ingente MD, DPDSAbstractBackground: Dermoscopy, a non-invasive diagnostic tool, has been proven to improve the diagnostic accuracy of vascular tumors since it can aid in...
A randomized, double-blind, comparative study on the safety and efficacy of virgin coconut (Cocos nucifera l.) oil against 1% hydrocortisone lotion as an anti-inflammatory and antipruritic preparation for mosquito reactions
Authors: Uy, Veronica S, MD; Gracia B. Teodosio, MD, FPDS; Ma. Teresita G. Gabriel, MD, FPDS; Mary Catherine T. Galang, MD; Mohammad Yoga A. Waskito, MD; Johannes F. Dayrit, MD, FPDS Abstract Background: Virgin coconut oil (VCO) has been reported...
Primary Cutaneous Anaplastic Large Cell Lymphoma (PC-ALCL) is a rare Non-Hodgkin lymphoma (NHL) representing approximately 9% of all cutaneous lymphomas.3 It usually manifests as a slow-growing, solitary tumor which has a tendency to regress spontaneously. However, metastasis is reported in 5-10% of cases.