Frederica Veronica Marquez-Protacio MDAuthors:Frederica Veronica Marquez-Protacio MD Abstract & CitationReferences Abstract Introduction: Histoplasmosis is a granulomatous infection caused by the fungus, Histoplasma capsulatum. The disseminated type can be the initial manifestation of HIV/AIDS. It may...
Carmella Jane C. Luis, MD; Grace Monica Ibaviosa, MD, Johannes F. Dayrit, MD, FPDS
Hansen’s disease (HD) is a chronic granulomatous disease principally affecting the skin and peripheral nervous system caused by Mycobacterium leprae. The incubation period varies from months to more than 30 years. The tuberculoid form of HD usually presents with a single hypoesthetic patch and skin biopsy shows epithelioid granulomas with absence of bacilli on Fite-Faraco stain. In contradistinction, lepromatous leprosy usually presents with numerous papules, plaques and nodules with induration of the ears and nose. Biopsy shows foamy granulomas with presence of acid-fast bacilli on Fite-Faraco stain.
Catherina Jessica Sutantoyo, MD, Johannes F. Dayrit, MD, FPDS, Ma. Teresita G. Gabriel, MD, FPDS Glen Purnomo, MD, Reynaldo L. Ugalde MD, FPDS
We report a case of eumycetoma in a Filipino patient who presented with a solitary reddish brown, moist, multinodular tumor on the dorsum of the left foot of 2 years duration. Biopsy with Periodic acid Schiff (PAS) & Gomori methenamine silver (GMS) staining, fungal culture, ultrasound and X-ray of the foot were done in our institution which confirmed the diagnosis of eumycetoma. The patient was successfully treated with itraconazole 400/day for 3 months, followed by 200mg/day for the succeeding 9 months, leading to complete resolution of the lesion leaving an atrophic hypopigmented scar. A high index of suspicion supported by diagnostic tests aided in the early detection of the disease which also resulted to complete resolution of the disease.
Kristy Elleza R. Evangelista, MD, and Johannes F. Dayrit, MD, FPDS
Tuberculosis verrucosa cutis (TVC) is a cutaneous form of paucibacillary tuberculosis in individuals with moderate to high degree of immunity to Mycobacterium tuberculosis infection. This report highlights that TVC may present with atypical morphology and mimic other etiologies of diffuse plantar keratoderma.