(Last Updated On: August 10, 2020)

Authors: Nel Muriel B. Lee, MD, Heirich Fevrier P. Manalili, MD, Johannes F. Dayrit, MD, FPDS


Introduction: Lichen Planus Pigmentosus (LPP) is a pigmentary disorder of unknown etiology, presenting with diffuse hyperpigmentation in sun-exposed areas.

Case report: We report a case of a 32-year-old healthy male with widespread lichen planus pigmentosus, treated with clobetasol dipropionate 0.05% ointment, tacrolimus 0.1% ointment, and lowdose isotretinoin (0.1 to 0.2 mkd) showing a decrease in the progression and hyperpigmentation of patches and plaques after six months.

Conclusion: Based on our case and recent studies, low-dose oral isotretinoin, in combination with topical tacrolimus and topical corticosteroids, may show promising outcomes in treating cases of widespread lichen planus pigmentosus.


Lee NMB, Manalili HFP, Dayrit JF. Widespread lichen planus pigmentosus in a 32-year-old Filipino male treated with low dose isotretinoin and topical tacrolimus. Journal of the Philippine Dermatological Society 2019, 29(1), 122-124


LPP, pigmentary, dermoscopy, isotretinoin

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