Authors: Nel Muriel B. Lee, MD, Heirich Fevrier P. Manalili, MD, Johannes F. Dayrit, MD, FPDS
Introduction: Lichen Planus Pigmentosus (LPP) is a pigmentary disorder of unknown etiology, presenting with diffuse hyperpigmentation in sun-exposed areas.
Case report: We report a case of a 32-year-old healthy male with widespread lichen planus pigmentosus, treated with clobetasol dipropionate 0.05% ointment, tacrolimus 0.1% ointment, and lowdose isotretinoin (0.1 to 0.2 mkd) showing a decrease in the progression and hyperpigmentation of patches and plaques after six months.
Conclusion: Based on our case and recent studies, low-dose oral isotretinoin, in combination with topical tacrolimus and topical corticosteroids, may show promising outcomes in treating cases of widespread lichen planus pigmentosus.
Lee NMB, Manalili HFP, Dayrit JF. Widespread lichen planus pigmentosus in a 32-year-old Filipino male treated with low dose isotretinoin and topical tacrolimus. Journal of the Philippine Dermatological Society 2019, 29(1), 122-124
LPP, pigmentary, dermoscopy, isotretinoin
2. Fine, Jo David, et al. “The Classification ofInherited Epidermolysis Bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis andClassification of EB.” The Classification of Inherited Epidermolysis Bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB. Jaad, June 2008.
3. Fine, Jo-David. “Inherited epidermolysis bullosa.” Orphanet journal of rare diseases 5.1 (2010): 12.
4. Gilliam, Anita C and Neil J. Korman Subepidermal Vesiculobullous Dermatitis. 1st ed. Cleveland,Ohio,USA: Department of Dermatology, Case Western ReserveUniversity/University Hospitals of Cleveland, 2015.
5. Haber, Richard M,et al. Hereditary Epidermolysis Bullosa. 1st ed. Toronto, Ontario, Canada: Journal of the American Academy of Dermatology, 1985.
6. Intong, Lizbeth RA, and Dédée F. Murrell. “Inherited epidermolysis bullosa: new diagnostic criteria and classification.” Clinics in dermatology 30.1 (2012): 70-77.
7. Murrell, Dédée F. Blistering Diseases. 1st ed. Berlin: Springler, 2015.
8. Pfendner EG, Bruckner AL. Epidermolysis Bullosa Simplex. Seattle (WA): University of Washington, Seattle; 1993-2016.
9. Siañez-González, C. Congenital Epidermolysis Bullosa: A Review. 1st ed. Mexico: Escuela de Medicina del Instituto Tecnológico y de Estudios Superiores de Monterrey, 2009.
Authors: Katrina Carmela M. Belen, MD, DPDS, Jasmin J.Jamora, MD, FPDS , Ma. Cecilia P. Ingente MD, DPDSAbstractBackground: Dermoscopy, a non-invasive diagnostic tool, has been proven to improve the diagnostic accuracy of vascular tumors since it can aid in...
A randomized, double-blind, comparative study on the safety and efficacy of virgin coconut (Cocos nucifera l.) oil against 1% hydrocortisone lotion as an anti-inflammatory and antipruritic preparation for mosquito reactions
Authors: Uy, Veronica S, MD; Gracia B. Teodosio, MD, FPDS; Ma. Teresita G. Gabriel, MD, FPDS; Mary Catherine T. Galang, MD; Mohammad Yoga A. Waskito, MD; Johannes F. Dayrit, MD, FPDS Abstract Background: Virgin coconut oil (VCO) has been reported...
Primary Cutaneous Anaplastic Large Cell Lymphoma (PC-ALCL) is a rare Non-Hodgkin lymphoma (NHL) representing approximately 9% of all cutaneous lymphomas.3 It usually manifests as a slow-growing, solitary tumor which has a tendency to regress spontaneously. However, metastasis is reported in 5-10% of cases.