Authors: Mara Padilla Evangelista-Huber MD
Abstract: The Methods section of a clinical trial report should provide information on the design, conduct, and analysis of the trial. The essential information that must be found in this section includes details about:
· Description of trial design including allocation ratio
· Eligibility criteria of participants
· Setting and location of the trial
· Formulation, dosage, timing, and duration of any intervention given
· Characteristics of any placebo, including how it was disguised
· ‘Usual care’ given to a control group, if any
· Who administered the intervention
· Definitions of primary and secondary outcomes
· Who assessed the outcomes
· Frequency and timing of outcome measurements
· Key elements of the sample size calculation and interim analyses
· Sequence generation, allocation concealment, and implementation
· Who was blinded after assignment to interventions (participants, care providers, those assessing outcomes) and how it was done
· Reporting a treatment effect and the measure of uncertainty around the effect estimate
· Subgroup analyses, if any
Evangelista-Huber MP. Writing the methods section in a clinical trial report. J Phil Dermatol Soc 2019, 28(1), 10-14
methods, research, dermatology
Authors: Katrina Carmela M. Belen, MD, DPDS, Jasmin J.Jamora, MD, FPDS , Ma. Cecilia P. Ingente MD, DPDSAbstractBackground: Dermoscopy, a non-invasive diagnostic tool, has been proven to improve the diagnostic accuracy of vascular tumors since it can aid in...
A randomized, double-blind, comparative study on the safety and efficacy of virgin coconut (Cocos nucifera l.) oil against 1% hydrocortisone lotion as an anti-inflammatory and antipruritic preparation for mosquito reactions
Authors: Uy, Veronica S, MD; Gracia B. Teodosio, MD, FPDS; Ma. Teresita G. Gabriel, MD, FPDS; Mary Catherine T. Galang, MD; Mohammad Yoga A. Waskito, MD; Johannes F. Dayrit, MD, FPDS Abstract Background: Virgin coconut oil (VCO) has been reported...
Primary Cutaneous Anaplastic Large Cell Lymphoma (PC-ALCL) is a rare Non-Hodgkin lymphoma (NHL) representing approximately 9% of all cutaneous lymphomas.3 It usually manifests as a slow-growing, solitary tumor which has a tendency to regress spontaneously. However, metastasis is reported in 5-10% of cases.